Question 20 / 27:  An endoscopy performed on a 58 year old woman on ibuprofen for arthritis reveals a large ulcer in

the antrum of the stomach. There are no endoscopic stigmata of bleeding. A biopsy is obtained

from the stomach for rapid urease testing and this is negative.

Which of the following best explains the pathogenesis of this ulcer?

A  Reduced blood supply to the stomach
B  H pylori infection
C  Excessive gastric acid production
D  Excessive gastrin production
E  Inhibition of prostaglandin synthesis
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Gastrointestinal Pathophysiology Exam 2005

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Attribution:  Laurence Scott Bailen, Tamsin Knox, Paul Abourjaily, Fredric D. Gordon,Marshall Kaplan,Andrew G. Plaut. PPY 222 Gastrointestinal Pathophysiology, Spring 2007. (Tufts University OpenCourseWare), http://ocw.tufts.edu/Course/47 (Accessed 3 May, 2014). License: Creative Commons BY-NC-SA
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