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This young adult experienced the acute onset of tender, enlarged lymph nodes in both groins.

10. lymphogranuloma venereum

A sexually transmitted infection caused by Chlamydia trachomatis . In this patient, affected lymph nodes above and below the inguinal fold created the “groove sign” bilaterally.Although not pathognomonic, this sign is characteristic of lymphogranuloma venereum and should immediately suggest the diagnosis.

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Source:  OpenStax, Images of memorable cases: 50 years at the bedside. OpenStax CNX. Dec 08, 2008 Download for free at http://cnx.org/content/col10449/1.7
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