Card 23 / 30: To impress your parents and show them that their tuition loan was worth it all, you begin to tell them all you learned about the sites of action of cannabinoids in the brain. Your recollection is a little foggy, however, as you still have a buzz from that very fine stuff you smoked last night. What are some of the things you are trying to recall? (circle all that apply)
A) tetrahydrocannabinol (also the active ingredient in marijuana) is normally synthesized by medium spiny neurons of the striatum
B) anandamide is a membrane-permeant cannabinoid which can diffuse from a postsynaptic neuron to a presynaptic terminal as a form of retrograde transmission
C) binding of anandamide to CB1 receptors potentiates voltage-gated Ca2+ channels, leading to more neurotransmitter release
D) cannabinoids inhibit GABA release by neurons of the nucleus accumbens, stimulating dopaminergic neurons of the ventral tegmental area
E) morphine inhibits GABA release by neurons of the nucleus accumbens, stimulating dopaminergic neurons of the ventral tegmental area

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