• Card 24 / 29: The following is from a 5 yr old horse with history of anorexia and emaciation. PCV: 43 (normal) CK 830 (470 normal) AST 350 (300 normal) SDH 4 (normal) ALP 710 (290 normal) GGT 72 (17 normal) Serum Bilirubin 10.5 (normal 2.1) What is the most likely differential?
    A) Anorexia
    B) Acute muscle necrosis
    C) Acute hepatocyte necrosis
    D) Cholestasis
    E) Hemolysis

    Answer:
    D) Cholestasis

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Explanation:

Yes, the horse is anorexic, but there is more evidence of other issues. Acute muscle necrosis- this would not effect bilirubin levels. Acute hepatocyte necrosis - the SDH is normal so this is not likely

Hemolysis- yes this is a differential for increased bilirubin but the PCV is normal.

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Kidney/Liver Biopath

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