Card 21 / 32: Chronic Borrelia burdorferi (Lyme’s disease) infection in dogs can predispose them to autoimmune disease. Why is this?
A) Chronic inflammation causes exposure of cryptic self antigen and release of high amounts of self antigen.
B) Chronic inflammation allows for epitope spreading
C) High levels of IFN-y cause strong macrophage activation that overrides immune suppression mechanisms.
D) All of the above

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