Card 11 / 14: A 45 year-old male came to you for consult due to a 3-week history of cough and progressive weight loss. Work-up revealed tuberculosis. He mentioned that he was also diagnosed with cirrhosis after consulting with his gastroenterologist a week ago and that all tests were normal. In starting anti-TB meds, which will you avoid?
A)
None. I will start the usual 4-drug regimen
B)
I will have to avoid at least 2 of the most hepatotoxic drugs
C)
I will not start a regimen with any hepatotoxic drug as he re mainsat risk for drug-induced liver injury
D)
I will avoid pyrazinamide as this is the most hepatotoxic among the anti-TB drugs
Answer:
A) None. I will start the usual 4-drug regimen
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