Card 10 / 16: How does NF-κB induce gene expression?
a.) A small, hydrophobic ligand binds to NF-κB, activating it.
b.) Phosphorylation of the inhibitor Iκ-B dissociates the complex between it and NF-κB, and allows NF-κB to enter the nucleus and stimulate transcription.
c.) NF-κB is phosphorylated and is then free to enter the nucleus and bind DNA.
d.) NF-κB is a kinase that phosphorylates a transcription factor that binds DNA and promotes protein production.

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