Card 10 / 22: Watch this video ( http://openstaxcollege.org/l/neurotrans ) to learn about the release of a neurotransmitter. The action potential reaches the end of the axon, called the axon terminal, and a chemical signal is released to tell the target cell to do something, either initiate a new action potential, or to suppress that activity. In a very short space, the electrical signal of the action potential is changed into the chemical signal of a neurotransmitter, and then back to electrical changes in the target cell membrane. What is the importance of voltage-gated calcium channels in the release of neurotransmitters?
Answer:
The action potential depolarizes the cell membrane of the axon terminal, which contains the voltage-gated Ca2+ channel. That voltage change opens the channel so that Ca2+ can enter the axon terminal. Calcium ions make it possible for synaptic vesicles to release their contents through exocytosis.
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