Question 1 / 30:  Three days into the hospitalization for an acute illness a CT scan is performed on a 32 year old woman. She initially presented to the emergency room with severe periumbilical

pain, nausea, and vomiting. She denied any alcohol use and was on no medications. She had previously been feeling well. She was treated with intravenous fluids and kept nothing by mouth. An initial ultrasound exam of the abdomen revealed gallstones within

the gallbladder and a mildly dilated common bile duct. Because her symptoms persisted and she developed a fever the CT scan was obtained.

Which of following statements best describes the pathophysiology of this condition?

A  Obstruction of the cystic duct due to gallstones
B  Activation of pancreatic enzymes within the pancreas
C  Obstruction of the pancreatic duct due to proteinaceous plugs
D  Reduction in pancreatic enzyme synthesis and secretion
E  Reduction in stimulation of intracellular calcium signaling pathways
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Gastrointestinal Pathophysiology Exam 2006

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Attribution:  Laurence Scott Bailen, Tamsin Knox, Paul Abourjaily, Fredric D. Gordon,Marshall Kaplan,Andrew G. Plaut. PPY 222 Gastrointestinal Pathophysiology, Spring 2007. (Tufts University OpenCourseWare), http://ocw.tufts.edu/Course/47 (Accessed 3 May, 2014). License: Creative Commons BY-NC-SA
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