2) Aerosol adenosine exposure induces a dose-related bronchioconstriction in patients with asthma and COPD but not in normal controls.
3) Non-selective adenosine receptor antagonists improve lung function and symptoms of asthma and COPD.
4) Activation of adenosine receptors subtypes involved in asthma and COPD have been shown to elicit pro-inflammatory responses.
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