Question 11 / 91:  First-pass metabolism refers to metabolism by....
A  the liver and gut
B  the liver only
C  the stomach, liver and gut
D  the gut only
E  the stomach only
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Explanation:

After the gut the drug goes through the hepatic portal vein to the liver where it's metabolised again and some drugs are only active when metabolised by the hepatocytes in the liver.

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Pharmacology (MCQ) [Excl. Nervous System]

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