Refer to book for diagram. 1) Binds to SUR1 receptors (only on B cells) 2) Closes K+ ATP channel 3) Depolarises membrane 4) Opens voltage-dependent/gated Ca2+ channel (V(D/G)CC) 5) Stimulates exocytosis of insulin
1) Binds to SUR1 receptors (only on B cells)
2) Closes K+ ATP channel
3) Depolarises membrane
4) Opens voltage-dependent/gated Ca2+ channel (V(D/G)CC)
5) Stimulates exocytosis of insulin
Pharmacology (Test) [Excluding Nervous System]
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