Explain how using a combination of two Madison Christian Micro Quest

Question 34 / 40: Explain how using a combination of two antimicrobial drugs helps prevent the development of spontaneously resistant mutants.

A All drugs work synergistically with each other-that is, their combined effects are far greater
than either could achieve individually. Two drugs together helps to eliminate microbes, even
if they have developed spontaneous mutations that would confer upon them resistance to the
drugs.

B It is highly unlikely that the microbe might spontaneously develop 2 specific mutations to
resist the effects of a pair of drugs. As such, even if one drug is resisted by the microbe,
the 2nd drug will eliminate the mutated microbe, thus preventing the development of spontaneously
resistant mutants overall.

C All drugs work antagonistically with each other-that is, their combined effects are far greater
than either could achieve individually. Two drugs together helps to eliminate microbes, even
if they have developed spontaneous mutations that would confer upon them resistance to the
drugs.

D Drugs can also select for mutations that will enhance the activity of another drug. So, each
of the paired drugs will help to select for spontaneous mutations that enhance the activity
of the other drug in the pair.

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