Question 6 / 10:  Epidemiologic studies examining exposure-disease relationships may be observational or interventional.

What is the essential difference between an interventional and an observational study design?

Answer: 
In an interventional study design the investigator intervenes to assign an

exposure to a study volunteer, such a treatment or procedure (by random or nonrandom

assignment) whereas in an observational study, the investigator merely

observes the exposure as it occurs in the volunteer without intervening.

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Descriptive Epidemiology Incidence Prevalence

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Attribution:  Janet, E.A. Forrester, Kwan Ho Kenneth Chui, Steven Cohen, Michael D. Kneeland, Alice Tang, David Tybor. Epidemiology and Biostatistics 2010. (Tufts University OpenCourseWare), http://ocw.tufts.edu/Course/65/ (Accessed 3 May, 2014). License: Creative Commons BY-NC-SA
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