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Card 10 / 32:
Drugs such as lidocaine and novocaine act as Na + channel blockers. In other words, they prevent sodium from moving across the neuronal membrane. Why would this particular effect make these drugs such effective local anesthetics?
The action potential is initiated by an influx of Na+ into the neuron. If this process is prevented, then no action potentials in neurons in a given area will occur. Therefore, any painful stimuli would not result in action potentials carrying that information to the brain.
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