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    Why do ions have a difficult time getting through plasma membranes despite their small size?

    Ions are charged, and consequently, they are hydrophilic and cannot associate with the lipid portion of the membrane. Ions must be transported by carrier proteins or ion channels.

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Source:  OpenStax, Ap biology - part 1: the cell. OpenStax CNX. Oct 02, 2014 Download for free at https://legacy.cnx.org/content/col11711/1.1
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