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    Explain how single nucleotide changes can have vastly different effects on protein function.

    Nucleotide changes in the third position of codons may not change the amino acid and would have no effect on the protein. Other nucleotide changes that change important amino acids or create or delete start or stop codons would have severe effects on the amino acid sequence of the protein.

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Source:  OpenStax, Cell biology. OpenStax CNX. Jan 04, 2014 Download for free at https://legacy.cnx.org/content/col11570/1.3
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