AA small, hydrophobic ligand binds to NF-κB, activating it.
BPhosphorylation of the inhibitor Iκ-B dissociates the complex between it and NF-κB, and allows NF-κB to enter the nucleus and stimulate transcription.
CNF-κB is phosphorylated and is then free to enter the nucleus and bind DNA.
DNF-κB is a kinase that phosphorylates a transcription factor that binds DNA and promotes protein production.