| << Chapter < Page | Chapter >> Page > |
This 25-year-old Caucasian woman complained of progressive headaches, visual difficulties, and darkening of her skin during thepreceding six months. Three years earlier, she had undergone bilateral adrenalectomy for treatment of Cushing’s disease.
Development of an ACTH-producing, rapidly growing, and often invasive pituitary tumor after bilateral adrenalectomy for Cushing’sdisease. The clinical manifestations are headache, visual field defects, external ophthalmoplegias, and ACTH-induced hyperpigmentation similar to that ofAddison’s disease.
The patient shown had generalized hyperpigmentation of her skin and mucosal surfaces, a large pituitary mass, bitemporal hemianopia,and palsies of the right 3rd and 6th cranial nerves. After transphenoidal resection of most of her pituitary tumor, coupled with postoperative radiationtherapy, her headaches resolved and her vision improved, but her ophthalmoplegias and hyperpigmentation did not change.
Notification Switch
Would you like to follow the 'Images of memorable cases: 50 years at the bedside' conversation and receive update notifications?
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|