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Assignments cover the topics discussed in the corresponding lecture sessions
| VN-LEC# |
MIT-LEC # |
ASSIGNMENTs |
SOLUTIONS |
| 3, 23, 29, 30, 32 |
1-5 |
Problem Set 1 (
PDF ) |
(
PDF ) |
| 18, 27, 29, 30 |
6-9 |
Problem Set 2 (
PDF ) |
(
PDF ) |
| 16, 20-23 |
11-15 |
Problem Set 3 (
PDF ) |
(
PDF ) |
| 24, 25 |
16-19 |
Problem Set 4 (
PDF ) |
(
PDF ) |
| 25-28 |
20-24 |
Problem Set 5 (
PDF ) |
(
PDF ) |
| 33, 28 |
25-30 |
Problem Set 6 (
PDF ) |
(
PDF ) |
| 31 |
31-35 |
Problem Set 7 (
PDF ) |
(
PDF ) |
A chromosome:
- A. is composed of amino acids
- B. is organized in the nucleus by histones
- C. is produced from RNA
- D. is present in 46 pairs in human cells
D. is present in 46 pairs in human cells
Genes:
- A. never function when they contain a mutation
- . directly produce proteins
- C. contain random pairings of nucleotides
- D. all of the above
- E. none of the above
During the process of transcription, genetic information is transferred from:
- A. DNA to RNA
- B. RNA to DNA
- C. DNA to protein
- D. Protein to RNA
A mutation that __________ production of a given _________ can manifest as clinical disease.
- A. increases/protein
- B. decreases/mRNA
- C. decreases/ protein
- D. increases/mRNA
- E. all of the above
- F. none of the above
A mutation occurs that disrupts the normal structure and function of hemoglobin. which of the following is true?
- A. clinical disease will develop based on the mutation alone.
- B. environmental factors can play a large role in the development of clinical disease.
- C. each person with the same mutation will follow the same clinical course.
- D. family members should be tested for this hereditary condition.
A. clinical disease will develop based on the mutation alone.
A germline mutation ___________ while a somatic mutation _______________.
- A. is never passed from parents to offspring // is present in all cells of one’s body
- B. is always passed from parents to offspring // is present in all cells of one’s body
- C. is present in all cells of one’s body // is never passed from parents to offspring
- D. is responsible for non-hereditary cancers // is not often a direct cause of inherited disease
C. is present in all cells of one’s body // is never passed from parents to offspring
A missense mutation
- A. does not affect protein structure
- B. does not affect protein function
- C. leads to substitution of an amino acid in a new place in the protein
- D. all of the above
- E. none of the above
C. leads to substitution of an amino acid in a new place in the protein
A nonsense mutation
- A. does not affect protein structure
- B. may not lead to clinical disease
- C. involves an inappropriate stop codon
- D. A and B
- E. A and C
- F. All of the above
C. involves an inappropriate stop codon
A silent mutation
- A. results in no change in protein structure/function
- B. can sometimes lead to clinical disease
- C. involves substitution of one amino acid for another
- D. A and C
- E. A and B
A. results in no change in protein structure/function
Source:
OpenStax, Genetics. OpenStax CNX. Jul 29, 2009 Download for free at http://cnx.org/content/col10782/1.1
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