Neurology Technician

Job Title: Laboratory Neuroscientist Technician

Location: Rockville MD 20852

Duration: 02 Years to Long term

Shift: Standard Shift (Mon to Fri) 40 Hours/Week

Onsite: Yes

Teleworking Eligible: Yes

This is with federal client

Overall Position Summary and Objectives:

• Developing an integrated clinical, basic, and translational research ecosystem that identifies and characterizes immunologic processes that causally contribute to psychiatric illness, starting with rare autoantibodies in neuropsychiatric disorders.

Min Education

• Bachelor's

Preferred Skills:

• Experience in CLIA-certified lab
• Experience in rodent handling and husbandry
• Expertise in cell line and primary cell culture
• Expertise in small rodent sacrifice, perfusion, cryopreservation, and paraffin embedding
• Expertise in immunostaining: immunofluorescence, DAB, and colorimetric
• Animal Handling: Non-human primates

Software:

• Power point
• MS Project
• MS Access

Field of Study:

• Microbiology
• Molecular Biology

Certifications & Licenses

• Clinical Laboratory Improvement Amendments (CLIA)

Statement of Work Details

• Plans, executes, and arranges laboratory experiments, new techniques and procedures; and performs laboratory techniques relating to scientific research.
• Draft and maintain standard operating procedures for antibody screens and testing

Operates laboratory machines and instruments; and prepares specimens and equipment for use.

• Maintain electronic bio specimen handling and testing logs Performs sample management and storage.
• Schedule regular maintenance of equipment logs and maintain performance logs Analyzes, documents and reports on all procedures performed.
• Ensure that reagents are made correctly and that expired reagents or defective products are replaced to ensure validity of results Maintains inventory of laboratory supplies.
• Cleans and sterilizes instruments, glassware and equipment.
• Immunostain rodent and/or NHP brain tissue with human CSF, serum/plasma, and commercial antibodies

Plan execute and arrange laboratory experiments, new techniques and procedures; and performs laboratory techniques relating to scientific research.

• Preparation of presentation slides and figures for outside investigators . Occasionally attend lab meetings of outside investigators Maintains inventory of laboratory supplies and initiates purchase orders.
• Assist in troubleshooting and calibrating various laboratory equipment and instruments. Collect, analyze and interpret data; prepare summaries and reports based on results and findings Performs routine equipment maintenance.
• Primary cell isolation and culture (neurons, astrocytes, oligodendrocytes, and mixed cell culture) . iPSC-derived neuronal cell differentiation and culture.
• Plan execute and arrange laboratory experiments, new techniques and procedures; and performs laboratory techniques relating to scientific research.
• Perform experiments on samples according to protocols.
• Logging of assay and experimental results in electronic laboratory notebook (Lab Archives)

Analyzes, documents and reports on all procedures performed and produces detailed reports for use by senior staff.

• Human protein array immunostaining (HuProt) and data processing.
• Performs advanced equipment maintenance.
• screening for autoantibodies in human biofluids (blood fractions and cerebrospinal fluid) using a variety of methods including rodent(and non-human primate) brain tissue immunostaining, human protein array, iPSC-derived neuronal culture and immunostaining, and (less commonly) immunoprecipitation mass spectrometry (IP-MS).

Trains staff in performing routine laboratory tests and procedures.

• Expected to engage with outside investigators for the purpose of interpreting and contextualizing preliminary results Provides insights and expertise and recommends new strategies and approaches.
• collaborate with in-house bio informaticists, biologists, and biochemists and have opportunities to mentor junior scientists
• contribute to the development of secondary neuroscientific questions stemming from antibody discovery research - present work at national conferences and publish their findings in peer-reviewed journals.