Molecular Biology Research Assistant, Translational Research 100

The Institute of Molecular and Clinical Ophthalmology Basel (IOB) is seeking a highly motivated Molecular Biology Research Assistant to join the Translational Group. IOB is a research institute combining basic and clinical research. Its mission is to drive innovations in understanding vision and its diseases and develop new therapies for vision loss. It is a place where your expertise will be valued, your abilities challenged, and your knowledge expanded.
The main goal of the Translational Group is to develop and bring new classes of therapies to the clinic. We specifically focus on gene therapy and base editing technologies to provide treatments for genetic vision loss. Our activities include developing gene editing assays, performing proof-of-concept studies in cells, organoids, retinal explants and animal models, optimizing lead candidate therapeutic agents, performing safety and biodistribution studies, characterizing and recruiting patients for clinical trials, developing clinical outcome measures, and preparing for regulatory authorization.

You will be participating in cutting-edge research and interact with people with different expertise!

Your position
Construct gene therapy vectors by molecular cloning;
Evaluate gene therapy efficiency using various molecular biology techniques, including PCR, qPCR, sequencing, Western-blot, and immunohistochemistry;
Perform cell-culture and cell-based assays;
Establish new techniques and protocols;
Support PhD students and postdocs in their research activities in the Translation Group;
General administrative support and maintenance of the lab;
Mouse work experience; managing transgenic animals, injections, tissue sampling, and processing;
Participate in the development and translation of cutting-edge gene therapeutic methods.

Your profile
Biologielaborant/in (or equivalent education) or Bachelor's/Master's Degree (or equivalent) in molecular biology or related field;
Strong background in molecular biology, with at least 3 years experience in basic molecular lab work (DNA, RNA purification, PCR, cloning, etc.);
LTK module 1, FELASA, or equivalent certification;
Independence in the planning, conducting, analysis, and troubleshooting of standard molecular biology experiments;
The candidate should be highly organized, precise, detail-oriented, and computer skilled;
Good written and verbal communication skills;
Fluency in oral and written English.

We offer you
Competitive salary among the academic world.
Five weeks of vacation for all employees, with increasing vacation days by age.
Paid maternity leave up to 16 weeks plus the opportunity to extend it through unpaid leave.
Opportunities for professional growth and development, including training and education support.
Family-friendly: we offer childcare subsidy and a family room.
The chance to be part of a groundbreaking research institute making a real impact in the field of medical science.
Additional discounts and benefits: e.g., cafeteria, access to the Uni Sport offerings at university Basel, and more.

Application / Contact

To apply, please submit your application through our recruiting platform ( Link ). For more information, visit iob.ch . If you have questions after applying, you can contact us by simply replying to the confirmation email you will receive.
Please note that we only accept applications via the recruiting portal.

Contact
IOB - Institute of Molecular and Clinical Ophthalmology Basel
Human Resources
Recruiting team
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