Annotation/Curation Analyst

The University Health Network, where 'above all else the needs of patients come first', encompasses Toronto General Hospital, Toronto Western Hospital, Princess Margaret Cancer Centre, Toronto Rehabilitation Institute and the Michener Institute of Education. The breadth of research, the complexity of the cases treated, and the magnitude of its educational enterprise has made UHN a national and international resource for patient care, research and education. With a long tradition of ground-breaking firsts and a purpose of 'Transforming lives and communities through excellence in care, discovery and learning', the University Health Network (UHN), Canada's largest research teaching hospital, brings together over 16,000 employees, more than 1,200 physicians, 8,000+ students, and many volunteers. UHN is a caring, creative place where amazing people are amazing the world.

Union:
Non-Union
Site:
Toronto General Hospital
Department:
Laboratory Medicine Program, Advanced Diagnostic
Work Model:
On-Site
Reports to:
Senior Manager, Advanced Diagnostics
Grade:
N0:
06
Hours:
37.5 hours per week
Salary:
$33.32 - $41.65 per hour
Shifts:
All Shifts 24/7
Status:
Permanent Full Time
Closing Date:
January 6, 2025

Position Summary
Join UHN's Laboratory Medicine Program, Canada's largest hospital diagnostic lab and a global leader in academic labs. With over 30 million tests per year and 1,300 outpatients served daily, we are at the forefront of pathology and clinical testing. Embrace innovation and contribute to ground-breaking research, education, and exemplary service. Join our dynamic team of 700 dedicated staff and play a pivotal role in shaping the future of laboratory medicine.

As an integral member of the Clinical Genomic team, the Annotation/Curation Analyst plays a key role in supporting the efforts of the Clinical Genome Diagnostics laboratory.

Duties

• Utilizing software tools, databases and primary literature to investigate the clinical relevance of variants detected by genetic methods including next-generation sequencing (NGS)
• Drafting concise variant interpretations
• Utilizing practical and theoretical knowledge for the analysis of NGS and other laboratory data, including somatic and germline testing
• Completing required database and reporting activities related to variant analyses
• Completing assigned workload in a manner to ensure the efficient operation of the clinical laboratory
• Participating in molecular profiling test development activities with laboratory technologists
• Maintaining quality control standards in assigned area
• Participating in communication activities to maintain and continually enhance the co-operation and coordination of services with other laboratory staff and with external lab clients
• Participating in professional development, teaching/education activities, safety and quality improvement programs to ensure excellence in the provision of services
• Adhering to Hospital and departmental mission and value statements while maintaining patient confidentiality

Qualifications

• Master's degree in Molecular Genetics or related discipline required at minimum
• 6 months minimum of relevant experience required
• Knowledge of and experience with molecular genetic variant assessment techniques
• Knowledge of and experience with the use of genetic databases / resources and software (e.g. HGMD, COSMIC, gnomAD, cBioPortal, CICiC, ClinVar)
• Knowledge of and experience with the theory and application of NGS platforms and NGS analysis
• Knowledge of the theory and practice of current NGS laboratory procedures, instruments, equipment and special techniques
• Excellent problem recognition and problem solving skills
• Effective organizational, time management and prioritization skills
• Excellent verbal and written communication skills
• Ability to learn quickly, take in and distill large amounts of information and apply scientific knowledge
• Scientific curiosity and interest to stay on top of emerging scientific data and trends as it pertains to the role
• Demonstrated ability to take initiative, multitask and think critically
• Ability to work independently and with cross-functional team members

Additional Information

In addition to working alongside some of the most talented and inspiring healthcare professionals in the world, UHN offers a wide range of benefits, programs and perks. It is the comprehensiveness of these offerings that makes it a differentiating factor, allowing you to find value where it matters most to you, now and throughout your career at UHN.

• Competitive offer packages
• Government organization and a member of the Healthcare of Ontario Pension Plan (HOOPP)
• Close access to Transit and UHN shuttle service
• A flexible work environment
• Opportunities for development and promotions within a large organization
• Additional perks (multiple corporate discounts including:
  travel, restaurants, parking, phone plans, auto insurance discounts, on-site gyms, etc.)

Current UHN employees must have successfully completed their probationary period, have a good employee record along with satisfactory attendance in accordance with UHN's attendance management program, to be eligible for consideration.

All applications must be submitted before the posting close date.

UHN uses email to communicate with selected candidates. Please ensure you check your email regularly.

Please be advised that a Criminal Record Check may be required of the successful candidate. Should it be determined that any information provided by a candidate be misleading, inaccurate or incorrect, UHN reserves the right to discontinue with the consideration of their application.

UHN is an equal opportunity employer committed to an inclusive recruitment process and workplace. Requests for accommodation can be made at any stage of the recruitment process. Applicants need to make their requirements known.

We thank all applicants for their interest, however, only those selected for further consideration will be contacted.