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Card 11 / 16: Why does increasing EDV increase contractility?
Answer:
Increasing EDV increases the sarcomeres' lengths within the cardiac muscle cells, allowing more cross bridge formation between the myosin and actin and providing for a more powerful contraction. This relationship is described in the Frank-Starling mechanism.
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Attribution:
OpenStax College. Anatomy & Physiology, OpenStax-CNX Web site. http://cnx.org/content/col11496/1.6/, Jun 11, 2014
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