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Card 22 / 85: Which of these are true of vesicle release?
A)
Cholera toxin and pertussis toxin inhibit neurotransmission by cleaving proteins of the SNARE complex.
B)
Synaptobrevin is the Ca2+ sensor triggered by Ca2+ influx through voltage-gated calcium channels.
C)
At a typical presynaptic terminal in the CNS, the readily releasable pool of vesicles numbers only 100-200.
D)
Ca2+ accumulation during multiple presynaptic action potentials causes facilitation of transmitter release.
E)
Presynaptic G-protein coupled receptors can inhibit transmitter release both by inhibiting voltage-gated Ca2+ channels and by activating potassium channels.
Answer:
D) Ca2+ accumulation during multiple presynaptic action potentials causes facilitation of transmitter release.
E) Presynaptic G-protein coupled receptors can inhibit transmitter release both by inhibiting voltage-gated Ca2+ channels and by activating potassium channels.
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Attribution:
Corey, David. HST.131 Introduction to Neuroscience, Fall 2005. (MIT OpenCourseWare: Massachusetts Institute of Technology), http://ocw.mit.edu/courses/health-sciences-and-technology/hst-131-introduction-to-neuroscience-fall-2005 (Accessed 12 Apr, 2014). License: Creative Commons BY-NC-SA
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