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Card 21 / 30: There is potassium channel made of KCNQ2 and KCNQ3 subunits, which is partly open at rest, and slowly opens more when depolarized. This channel is closed by acetylcholine or muscarine, and so current through this channel is called the M-current. Which are likely to be true about the M-current?
A)
acetylcholine probably acts on the current through a second messenger
B)
application of acetylcholine to dendrites containing KCNQ2/3 will increase thelength constant of the dendrite
C)
cells with KCNQ2/3 will have a harder time firing a burst of action pote than a single action potential
D)
application of acetylcholine to a presynaptic terminal containing KCNQ2/3 will decrease vesicle release
Answer:
A) acetylcholine probably acts on the current through a second messenger
B) application of acetylcholine to dendrites containing KCNQ2/3 will increase thelength constant of the dendrite
C) cells with KCNQ2/3 will have a harder time firing a burst of action pote than a single action potential
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Attribution:
Corey, David. HST.131 Introduction to Neuroscience, Fall 2005. (MIT OpenCourseWare: Massachusetts Institute of Technology), http://ocw.mit.edu/courses/health-sciences-and-technology/hst-131-introduction-to-neuroscience-fall-2005 (Accessed 12 Apr, 2014). License: Creative Commons BY-NC-SA
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