Card 10 / 39: A 24 year-old male without co-morbidities, was admitted for abrupt onset of fever, anorexia, nausea and vomiting accompanied by headache 5 days after swimming in the river. He was obtunded, but without focal neurologic signs. His condition rapidly progressed to coma. What is the most likely pathogenesis for his condition?
A)
The organism gains entry through the lower respiratory tract and enters the circulation before disseminating to the brain
B)
CNS invasion occurs after nasal inoculation with the organism, which disrupts the olfactory mucosa
C)
The organism end enters the circulation before disseminating to the brainnters through ulcerated skin a
D)
None of the above
Answer:
B) CNS invasion occurs after nasal inoculation with the organism, which disrupts the olfactory mucosa
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