Card 17 / 30: For channels in the open conformation, we frequently approximate I(V) relationships as Ohmic, but we know that they are not strictly linear. Which of the following contribute to nonlinearities in open-channel I(V) relationships?
A) Voltage-dependent gating
B) Membrane capacitance
C) Voltage-dependent block of pores by intracellular or extracellular ions.
D) Differences in the concentration of charge carriers across the membrane.
E) Voltage-dependent changes in permeability of the lipid bilayer

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