Card 15 / 30: A typical mammalian CNS synapse differs from the neuromuscular junction (NMJ) in the following ways (circle all that apply):
A)
A CNS presynaptic terminal typically releases 1 vesicle per action potential while a NMJ terminal releases hundreds.
B)
Acetylcholine is hydrolyzed by acetylcholinesterase in the cleft at the NMJ, while glutamate is cleaved by glutamate hydrolase in the cleft in CNS synapses.
C)
NMJ synapses have dense-core vesicles while CNS vesicles are usually clear.
D)
CNS, but not NMJ presynaptic terminals can be postsynaptic to inhibitory neurons.
E)
A muscle cell is innervated by a single motor neuron while a CNS neuron can be postsynaptic to many neurons.
Answer:
A) A CNS presynaptic terminal typically releases 1 vesicle per action potential while a NMJ terminal releases hundreds.
D) CNS, but not NMJ presynaptic terminals can be postsynaptic to inhibitory neurons.
E) A muscle cell is innervated by a single motor neuron while a CNS neuron can be postsynaptic to many neurons.
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