• Card 3 / 34: A 75 year-old woman complains of severe chest pain. A cardiac evaluation is unrevealing. An upper endoscopy shows erythema and linear ulcerations in the distal esophagus. Her only medication is synthroid (thyroid hormone replacement). Which of the following is the most likely explanation for these endoscopic findings?
    1.) Caustic injury
    2.) Cytomegalovirus infection
    3.) Mucosal injury from bile
    4.) Mucosal injury from acid
    5.) Mucosal injury from a foreign body

    Answer:
    4.) Mucosal injury from acid

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Explanation:

Causes of reflux esophagitis. Most commonly due to acid reflux. Other answers are not likely based on the clinical history.

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Gastrointestinal Pathophysiology Self-Assessment

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Attribution:  Laurence Scott Bailen, Tamsin Knox, Paul Abourjaily, Fredric D. Gordon,Marshall Kaplan,Andrew G. Plaut. PPY 222 Gastrointestinal Pathophysiology, Spring 2007. (Tufts University OpenCourseWare), http://ocw.tufts.edu/Course/47 (Accessed 3 May, 2014). License: Creative Commons BY-NC-SA
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