• Card 32 / 34: A 60 year-old woman with a long-standing history of cirrhosis develops esophageal varices and hepatic encephalopathy. An abdominal ultrasound reveals thrombosis of the portal vein. Which of the following pressure measurements would you most likely expect to find?
    1.) Normal hepatic vein pressure gradient
    2.) Elevated wedged hepatic vein pressure
    3.) Elevated free hepatic vein pressure
    4.) Elevated hepatic vein pressure gradient
    5.) Low wedged hepatic vein pressure

    Answer:
    1.) Normal hepatic vein pressure gradient

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Explanation:

Portal vein thrombosis is a cause of pre-hepatic portal hypertension. In this situation the hepatic vein pressure gradient is normal because the wedged and free hepatic vein pressures are normal.

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Gastrointestinal Pathophysiology Self-Assessment

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Attribution:  Laurence Scott Bailen, Tamsin Knox, Paul Abourjaily, Fredric D. Gordon,Marshall Kaplan,Andrew G. Plaut. PPY 222 Gastrointestinal Pathophysiology, Spring 2007. (Tufts University OpenCourseWare), http://ocw.tufts.edu/Course/47 (Accessed 3 May, 2014). License: Creative Commons BY-NC-SA
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