• Card 28 / 34: Which of the following most likely explains the patients liver function tests?A 55 year old man is jaundiced. His total bilirubin is 8.4 mg/dl and his ALT is 125, AST is 205, alkaline phosphatase is normal. An abdominal ultrasound is normal.
    01.) Bile duct obstruction
    02.) Acute alcoholic hepatitis
    03.) Acute acetaminophen overdose
    04.) Acute hepatitis A
    05.) Acute hepatitis B
    06.) Acute hepatitis C
    07.) Alpha-1-antitrypsin deficiency
    08.) Primary biliary cirrhosis
    09.) Hemochromatosis
    10.) Wilson’s disease
    11.) Acute hepatitis E
    12.) Autoimmune hepatitis

    Answer:
    02.) Acute alcoholic hepatitis

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Explanation:

AST>ALT pattern typical of acute alcoholic hepatitis.

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Gastrointestinal Pathophysiology Self-Assessment

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Attribution:  Laurence Scott Bailen, Tamsin Knox, Paul Abourjaily, Fredric D. Gordon,Marshall Kaplan,Andrew G. Plaut. PPY 222 Gastrointestinal Pathophysiology, Spring 2007. (Tufts University OpenCourseWare), http://ocw.tufts.edu/Course/47 (Accessed 3 May, 2014). License: Creative Commons BY-NC-SA
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