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Compared to invertebrates, vertebrate nervous systems are more complex, centralized, and specialized. While there is great diversity among different vertebrate nervous systems, they all share a basic structure: a CNS that contains a brain and spinal cord and a PNS made up of peripheral sensory and motor nerves. One interesting difference between the nervous systems of invertebrates and vertebrates is that the nerve cords of many invertebrates are located ventrally whereas the vertebrate spinal cords are located dorsally. There is debate among evolutionary biologists as to whether these different nervous system plans evolved separately or whether the invertebrate body plan arrangement somehow “flipped” during the evolution of vertebrates.
The nervous system is made up of neurons , specialized cells that can receive and transmit chemical or electrical signals, and glia , cells that provide support functions for the neurons by playing an information processing role that is complementary to neurons. A neuron can be compared to an electrical wire—it transmits a signal from one place to another. Glia can be compared to the workers at the electric company who make sure wires go to the right places, maintain the wires, and take down wires that are broken. This analogy might be oversimplified, however; recent evidence suggests that glial cells also usurp some of the signaling functions of neurons.
The nervous system of the common laboratory fly, Drosophila melanogaster , contains around 100,000 neurons, the same number as a lobster. This number compares to 75 million in the mouse and 300 million in the octopus. A human brain contains around 86 billion neurons. Despite these very different numbers, the nervous systems of these animals control many of the same behaviors—from basic reflexes to more complicated behaviors like finding food and courting mates. The ability of neurons to communicate with each other as well as with other types of cells underlies all of these behaviors.
There is great diversity in the types of neurons and glia that are present in different parts of the nervous system. There are three major functional types of neurons (and many different morphological types), and they share several important cellular components. But neurons are also highly specialized—different types of neurons have different sizes and shapes that relate to their functional roles. There are also several types of glial cells (astroglia, oligodendrocytes, Schwann cells, etc.) each with different functions.
Like other cells, each neuron has a cell body (or soma) that contains a nucleus, smooth and rough endoplasmic reticulum, Golgi apparatus, mitochondria, and other cellular components. Neurons also contain unique structures, illustrated in [link] for receiving and sending the electrical signals that make neuronal communication possible. Dendrites are tree-like structures that extend away from the cell body to receive messages from other neurons at specialized junctions called synapses . Although some neurons do not have any dendrites, some types of neurons have multiple dendrites.
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