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The medicinal properties of plants have been known to human societies since ancient times. There are references to the use of plants’ curative properties in Egyptian, Babylonian, and Chinese writings from 5,000 years ago. Many modern synthetic therapeutic drugs are derived or synthesized de novo from plant secondary metabolites. It is important to note that the same plant extract can be a therapeutic remedy at low concentrations, become an addictive drug at higher doses, and can potentially kill at high concentrations. [link] presents a few drugs, their plants of origin, and their medicinal applications.
Plant Origin of Medicinal Compounds and Medical Applications | ||
---|---|---|
Plant | Compound | Application |
Deadly nightshade ( Atropa belladonna ) | Atropine | Dilate eye pupils for eye exams |
Foxglove ( Digitalis purpurea ) | Digitalis | Heart disease, stimulates heart beat |
Yam ( Dioscorea spp.) | Steroids | Steroid hormones: contraceptive pill and cortisone |
Ephedra ( Ephedra spp.) | Ephedrine | Decongestant and bronchiole dilator |
Pacific yew ( Taxus brevifolia ) | Taxol | Cancer chemotherapy; inhibits mitosis |
Opium poppy ( Papaver somniferum ) | Opioids | Analgesic (reduces pain without loss of consciousness) and narcotic (reduces pain with drowsiness and loss of consciousness) in higher doses |
Quinine tree ( Cinchona spp.) | Quinine | Antipyretic (lowers body temperature) and antimalarial |
Willow ( Salix spp.) | Salicylic acid (aspirin) | Analgesic and antipyretic |
Pharmacognosy is the branch of pharmacology that focuses on medicines derived from natural sources. With massive globalization and industrialization, there is a concern that much human knowledge of plants and their medicinal purposes will disappear with the cultures that fostered them. This is where ethnobotanists come in. To learn about and understand the use of plants in a particular culture, an ethnobotanist must bring in knowledge of plant life and an understanding and appreciation of diverse cultures and traditions. The Amazon forest is home to an incredible diversity of vegetation and is considered an untapped resource of medicinal plants; yet, both the ecosystem and its indigenous cultures are threatened with extinction.
To become an ethnobotanist, a person must acquire a broad knowledge of plant biology, ecology and sociology. Not only are the plant specimens studied and collected, but also the stories, recipes, and traditions that are linked to them. For ethnobotanists, plants are not viewed solely as biological organisms to be studied in a laboratory, but as an integral part of human culture. The convergence of molecular biology, anthropology, and ecology make the field of ethnobotany a truly multidisciplinary science.
Biodiversity ensures a resource for new food crops and medicines. Plant life balances ecosystems, protects watersheds, mitigates erosion, moderates climate and provides shelter for many animal species. Threats to plant diversity, however, come from many angles. The explosion of the human population, especially in tropical countries where birth rates are highest and economic development is in full swing, is leading to human encroachment into forested areas. To feed the larger population, humans need to obtain arable land, so there is massive clearing of trees. The need for more energy to power larger cities and economic growth therein leads to the construction of dams, the consequent flooding of ecosystems, and increased emissions of pollutants. Other threats to tropical forests come from poachers, who log trees for their precious wood. Ebony and Brazilian rosewood, both on the endangered list, are examples of tree species driven almost to extinction by indiscriminate logging.
The number of plant species becoming extinct is increasing at an alarming rate. Because ecosystems are in a delicate balance, and seed plants maintain close symbiotic relationships with animals—whether predators or pollinators—the disappearance of a single plant can lead to the extinction of connected animal species. A real and pressing issue is that many plant species have not yet been catalogued, and so their place in the ecosystem is unknown. These unknown species are threatened by logging, habitat destruction, and loss of pollinators. They may become extinct before we have the chance to begin to understand the possible impacts from their disappearance. Efforts to preserve biodiversity take several lines of action, from preserving heirloom seeds to barcoding species. Heirloom seeds come from plants that were traditionally grown in human populations, as opposed to the seeds used for large-scale agricultural production. Barcoding is a technique in which one or more short gene sequences, taken from a well-characterized portion of the genome, are used to identify a species through DNA analysis.
Angiosperm diversity is due in part to multiple interactions with animals. Herbivory has favored the development of defense mechanisms in plants, and avoidance of those defense mechanism in animals. Pollination (the transfer of pollen to a carpel) is mainly carried out by wind and animals, and angiosperms have evolved numerous adaptations to capture the wind or attract specific classes of animals.
Plants play a key role in ecosystems. They are a source of food and medicinal compounds, and provide raw materials for many industries. Rapid deforestation and industrialization, however, threaten plant biodiversity. In turn, this threatens the ecosystem.
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