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    Why is the receptor the important element determining the effect a neurotransmitter has on a target cell?

    Different neurotransmitters have different receptors. Thus, the type of receptor in the postsynaptic cell is what determines which ion channels open. Acetylcholine binding to the nicotinic receptor causes cations to cross the membrane. GABA binding to its receptor causes the anion chloride to cross the membrane.

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Source:  OpenStax, Anatomy & Physiology. OpenStax CNX. Feb 04, 2016 Download for free at http://legacy.cnx.org/content/col11496/1.8
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