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    Darcy and Raul are having difficulty conceiving a child. Darcy ovulates every 28 days, and Raul’s sperm count is normal. If we could observe Raul’s sperm about an hour after ejaculation, however, we’d see that they appear to be moving only sluggishly. When Raul’s sperm eventually encounter Darcy’s oocyte, they appear to be incapable of generating an adequate acrosomal reaction. Which process has probably gone wrong?

    The process of capacitation appears to be incomplete. Capacitation increases sperm motility and makes the sperm membrane more fragile. This enables it to release its digestive enzymes during the acrosomal reaction. When capacitation is inadequate, sperm cannot reach the oocyte membrane.

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Source:  OpenStax, Anatomy & Physiology. OpenStax CNX. Feb 04, 2016 Download for free at http://legacy.cnx.org/content/col11496/1.8
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