12.1 Basic structure and function of the nervous system  (Page 63/38)

The picture you have in your mind of the nervous system probably includes the brain    , the nervous tissue contained within the cranium, and the spinal cord    , the extension of nervous tissue within the vertebral column. That suggests it is made of two organs—and you may not even think of the spinal cord as an organ—but the nervous system is a very complex structure. Within the brain, many different and separate regions are responsible for many different and separate functions. It is as if the nervous system is composed of many organs that all look similar and can only be differentiated using tools such as the microscope or electrophysiology. In comparison, it is easy to see that the stomach is different than the esophagus or the liver, so you can imagine the digestive system as a collection of specific organs.

The central and peripheral nervous systems

The nervous system can be divided into two major regions: the central and peripheral nervous systems. The central nervous system (CNS)    is the brain and spinal cord, and the peripheral nervous system (PNS)    is everything else ( [link] ). The brain is contained within the cranial cavity of the skull, and the spinal cord is contained within the vertebral cavity of the vertebral column. It is a bit of an oversimplification to say that the CNS is what is inside these two cavities and the peripheral nervous system is outside of them, but that is one way to start to think about it. In actuality, there are some elements of the peripheral nervous system that are within the cranial or vertebral cavities. The peripheral nervous system is so named because it is on the periphery—meaning beyond the brain and spinal cord. Depending on different aspects of the nervous system, the dividing line between central and peripheral is not necessarily universal.

Central and peripheral nervous system

Nervous tissue, present in both the CNS and PNS, contains two basic types of cells: neurons and glial cells. A glial cell    is one of a variety of cells that provide a framework of tissue that supports the neurons and their activities. The neuron    is the more functionally important of the two, in terms of the communicative function of the nervous system. To describe the functional divisions of the nervous system, it is important to understand the structure of a neuron. Neurons are cells and therefore have a soma    , or cell body, but they also have extensions of the cell; each extension is generally referred to as a process    . There is one important process that every neuron has called an axon    , which is the fiber that connects a neuron with its target. Another type of process that branches off from the soma is the dendrite    . Dendrites are responsible for receiving most of the input from other neurons. Looking at nervous tissue, there are regions that predominantly contain cell bodies and regions that are largely composed of just axons. These two regions within nervous system structures are often referred to as gray matter    (the regions with many cell bodies and dendrites) or white matter    (the regions with many axons). [link] demonstrates the appearance of these regions in the brain and spinal cord. The colors ascribed to these regions are what would be seen in “fresh,” or unstained, nervous tissue. Gray matter is not necessarily gray. It can be pinkish because of blood content, or even slightly tan, depending on how long the tissue has been preserved. But white matter is white because axons are insulated by a lipid-rich substance called myelin    . Lipids can appear as white (“fatty”) material, much like the fat on a raw piece of chicken or beef. Actually, gray matter may have that color ascribed to it because next to the white matter, it is just darker—hence, gray.